Revitalizing Japan's biomedical ecosystem: Policy initiatives, challenges, and future directions

Okuyama R

Drug Discov Ther. 2025; 19(4):214-219.

DOI: 10.5582/ddt.2025.01056

Serum lipid levels serve as predictors for osteoporosis or osteopenia in postmenopausal women: A meta-analysis of observational studies

Ye FJ, Zhang YL, Chen ZQ, Zhou J, Wang J, Fu XY, Qi Q, Wang L

Drug Discov Ther. 2025; 19(4):220-229.

DOI: 10.5582/ddt.2025.01067

Bovine lactoferrin intake prevents hepatic injury in a mouse model of non-alcoholic steatohepatitis induced by choline and methionine deficiency

Aoki R, Ishido K, Furukawa M, Ishibashi Y, Nozaki S, Ito N, Toho M, Nagashima D, Izumo N

Drug Discov Ther. 2025; 19(4):230-236.

DOI: 10.5582/ddt.2025.01047

Piezo1 mediates calcium ion influx, glucose transporter 4 translocation, and glucose uptake in adipocytes under low-frequency vibration

Huang DZ, Haba D, Tomida S, Takizawa C, Qin Q, Kataoka Y, Mugita Y, Sanada H, Nakagami G

Drug Discov Ther. 2025; 19(4):237-244.

DOI: 10.5582/ddt.2025.01061

Evaluation of electrospun composite biomaterial and porcine small intestine submucosa patch in open inguinal herniorrhaphy: A prospective, randomized, single-blind, controlled, multicenter, 72-month clinical study

Qiu ZY, Fang L, Li SJ, Tang JX, Pang Y, Wang J, Zhou J, Wang L, Chen L

Drug Discov Ther. 2025; 19(4):245-252.

DOI: 10.5582/ddt.2025.01066

Switching from originator infliximab to biosimilar infliximab in Japanese patients with rheumatoid arthritis achieving clinical remission (the IFX-SIRIUS study I): An interventional, multicenter, open-label, single-arm clinical trial with clinical, ultrasound and biomarker assessments

Shimizu T, Kawashiri SY, Koga T, Kiya R, Morita M, Kuroda S, Tashiro S, Sato S, Yano H, Asano T, Saito K, Yoshitama T, Ueki Y, Eiraku N, Yamada Y, Okano T, Ushio Y, Dobashi H, Itami T, Tomita D, Nozaki Y, Hosogaya N, Yamamoto H, Kawakami A

Drug Discov Ther. 2025; 19(4):253-261.

DOI: 10.5582/ddt.2025.01044

Anti-Mycobacterium avium complex activities of streptcytosine analogs from a marine actinomycete as nucleoside antibiotics

Oshima N, Yagi A, Yamazaki H, Uchida R

Drug Discov Ther. 2025; 19(4):262-266.

DOI: 10.5582/ddt.2025.01052

Implementation and evaluation of a structured lecture-based training program for early-career pharmacists

Nonomiya Y, Nakamura M, Nakamura T, Yamaguchi M

Drug Discov Ther. 2025; 19(4):267-270.

DOI: 10.5582/ddt.2025.01063

A pilot study investigating the efficiency of an Internet of things (IOT)-aided warehouse management system in the management of consumables for the operating room in a Chinese setting

Zhang GM, Wang Q, Zhao L, Zhang H, Lin J, Asakawa T

Drug Discov Ther. 2025; 19(4):271-274.

DOI: 10.5582/ddt.2025.01068

Telisotuzumab vedotin: The first-in-class c-Met-targeted antibody-drug conjugate granted FDA accelerated approval for treatment of non-squamous non-small cell lung cancer (NSCLC)

Zhao CR, Lu DR, Gao JJ

Drug Discov Ther. 2025; 19(4):275-276.

DOI: 10.5582/ddt.2025.01058