Drug Discov Ther. 2020;14(4):171-176. (DOI: 10.5582/ddt.2020.03059)

Review of current clinical management guidelines for COVID-19 with special reference to India

Kumar R, Vinod KS, Mittal A, Adhikari SD, Gupta N


The healthcare sector has been overwhelmed by the global rise in the number of COVID-19 cases. The primary care physicians at the forefront of this pandemic are being provided with multiple guidelines (state, national, international). The aim of this review was to examine the existing guidelines for congruence and critically analyze them in light of current evidence. A discordance was noted between the national and state guidelines with respect to indication, duration and dosage of antivirals, steroids/immunomodulators, anticoagulation and convalescent plasma. The lack of concordance between various guidelines mandates the need for a unified national guideline that is regularly updated.

KEYWORDS: Coronavirus disease 19, hydroxychloroquine, remdesivir, dexamethasone, tocilizumab, convalescent plasma

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