1. Scope of Articles
2. Submission types
3. Manuscript preparation
4. Figure preparation
5. Online submission
6. Accepted manuscripts
2. Submission types
3. Manuscript preparation
4. Figure preparation
5. Online submission
6. Accepted manuscripts
1. Scope of Articles
Drug Discoveries & Therapeutics mainly publishes articles related to basic and clinical pharmaceutical research such as pharmaceutical and therapeutical chemistry, pharmacology, pharmacy, pharmacokinetics, industrial pharmacy, pharmaceutical manufacturing, pharmaceutical technology, drug delivery, toxicology, and traditional herb medicine. Studies on drug-related fields such as biology, biochemistry, physiology, microbiology, and immunology are also within the scope of this journal.
2. Submission types
Original Articles should be reports new, significant, innovative, and original findings. An Article should contain the following sections: Title page, Abstract, Introduction, Materials and Methods, Results, Discussion, Acknowledgments, References, Figure legends, and Tables. There are no specific length restrictions for the overall manuscript or individual sections. However, we expect authors to present and discuss their findings concisely.
Brief Reports should be short and clear reports on new original findings and not exceed 4000 words with no more than two display items. Drug Discoveries & Therapeutics encourages younger researchers and doctors to report their research findings. Case reports are included in this category. A Brief Report contains the same sections as an Original Article, but Results and Discussion sections must be combined.
Reviews should include educational overviews for general researchers and doctors, and review articles for more specialized readers.
News articles should not exceed 500 words including one display item. These articles should function as an international news source with regard to topics in the life and social sciences and medicine. Submissions are not restricted to journal staff - anyone can submit news articles on subjects that would be of interest to Drug Discoveries & Therapeutics’ readers.
Letters discuss material published in Drug Discoveries & Therapeutics in the last 6 months or issues of general interest. Letters should not exceed 800 words and 6 references.
3. Manuscript preparation
Preparation of text. Manuscripts should be written in correct American English and submitted as a Microsoft Word (.doc) file in a single-column format. Manuscripts must be paginated and double-spaced throughout. Use Symbol font for all Greek characters. Do not import the figures into the text file but indicate their approximate locations directly on the manuscript. The manuscript file should be smaller than 5 MB in size.
Title page. The title page must include 1) the title of the paper, 2) name(s) and affiliation(s) of the author(s), 3) a statement indicating to whom correspondence and proofs should be sent along with a complete mailing address, telephone/fax numbers, and e-mail address, and 4) up to five key words or phrases.
Abstract. A one-paragraph abstract consisting of no more than 250 words must be included. It should state the purpose of the study, basic procedures used, main findings, and conclusions.
Abbreviations. All nonstandard abbreviations must be listed in alphabetical order, giving each abbreviation followed by its spelled-out version. Spell out the term upon first mention and follow it with the abbreviated form in parentheses. Thereafter, use the abbreviated form.
Introduction. The introduction should be a concise statement of the basis for the study and its scientific context.
Materials and Methods. Subsections under this heading should include sufficient instruction to replicate experiments, but well-established protocols may be simply referenced. Drug Discoveries & Therapeutics endorses the principles of the Declaration of Helsinki and expects that all research involving humans will have been conducted in accordance with these principles. All laboratory animal studies must be approved by the authors’ Institutional Review Board(s).
Results. The results section should provide details of all of the experiments that are required to support the conclusions of the paper. If necessary, subheadings may be used for an orderly presentation. All figures, tables, and photographs must be referred in the text.
Discussion. The discussion should include conclusions derived from the study and supported by the data. Consideration should be given to the impact that these conclusions have on the body of knowledge in which context the experiments were conducted. In Brief Reports, Results and Discussion sections must be combined.
Acknowledgments. All funding sources should be credited in the Acknowledgments section. In addition, people who contributed to the work but who do not fit the criteria for authors should be listed along with their contributions.
References. References should be numbered in the order in which they appear in the text. Cite references in text using a number in parentheses. Citing of unpublished results and personal communications in the reference list is not recommended but these sources may be mentioned in the text. For all references, list all authors, but if there are more than fifteen authors, list the first three authors and add “et al.” Abbreviate journal names as they appear in PubMed. Web references can be included in the reference list.
Example 1: Hamamoto H, Kamura K, Razanajatovo IM, Murakami K, Santa T, Sekimizu K. Effects of molecular mass and hydrophobicity on transport rates through non-specific pathways of the silkworm larva midgut. Int J Antimicrob Agents. 2005; 26:38-42.
Example 2: Zhao X, Jing ZP, Xiong J, Jiang SJ. Suppression of experimental abdominal aortic aneurysm by tetracycline: a preliminary study. Chin J Gen Surg. 2002; 17:663-665. (in Chinese)
Example 3: Mizuochi T. Microscale sequencing of N-linked oligosacchaides of glycoproteins using hydrazinolysis, Bio-Gel P-4, and sequential exoglycosidase digestion. In: Methods in Molecular Biology: Vol. 14 Glycoprotein analysis in biomedicine (Hounsell T, ed.). Humana Press, Totowa, NJ, USA, 1993; pp. 55-68.
Example 4: Drug Discoveries & Therapeutics. Hot topics & news: China-Japan Medical Workshop on Drug Discoveries and Therapeutics 2007. http://www.ddtjournal.com/hotnews.php (accessed July 1, 2007).
Figure legends. Include a short title and a short explanation. Methods described in detail in the Materials and methods section should not be repeated in the legend. Symbols used in the figure must be explained. The number of data points represented in a graph must be indicated.
Tables. All tables should have a concise title and be typed double-spaced on pages separate from the text. Do not use vertical rules. Tables should be numbered with Arabic numerals consecutively in accordance with their appearance in the text. Place footnotes to tables below the table body and indicate them with lowercase superscript letters.
Language Editing. Manuscripts submitted by authors whose primary language is not English should have their work proofread by a native English speaker before submission. The Editing Support Organization can provide English proofreading, Japanese-English translation, and Chinese-English translation services to authors who want to publish in Drug Discoveries & Therapeutics and need assistance before submitting an article. Authors can contact this organization directly at http://www.iacmhr.com/iac-eso .
IAC-ESO was established in order to facilitate manuscript preparation by researchers whose native language is not English and to help edit work intended for international academic journals. Quality revision, translation, and editing services are offered by our staff, who are native speakers of particular languages and who are familiar with academic writing and journal editing in English.
4. Figure preparation
All figures should be clear and cited in numerical order in the text. Figures must fit a one- or two-column format on the journal page: 8.3 cm (3.3 in.) wide for a single column; 17.3 cm (6.8 in.) wide for a double column; maximum height: 24.0 cm (9.5 in.). Only use the following fonts in the figure: Arial and Helvetica. Provide all figures as separate files. Acceptable file formats are JPEG and TIFF. Please note that files saved in JPEG or TIFF format in PowerPoint lack sufficient resolution for publication. Each Figure file should be smaller than 10 MB in size. Do not compress files. A fee is charged for a color illustration or photograph.
5. Online submission
Manuscripts should be submitted to Drug Discoveries & Therapeutics online at http://www.ddtjournal.com. The manuscript file should be smaller than 10 MB in size. If for any reason you are unable to submit a file online, please contact the Editorial Office by e-mail:
.Editorial and Head Office
Wei TANG, MD PhD
Executive Editor
Pearl City Koishikawa 603
2-4-5 Kasuga, Bunkyo-ku
Tokyo 112-0003
Japan
Tel: 03-5840-9697
Fax: 03-5840-9698
E-mail:

Cover letter. A cover letter from the corresponding author including the following information must accompany the submission: name, address, phone and fax numbers, and e-mail address of the corresponding author. This should include a statement affirming that all authors concur with the submission and that the material submitted for publication has not been previously published and is not under consideration for publication elsewhere and a statement regarding conflicting financial interests.
Authors may recommend up to three qualified reviewers other than members of Editorial board. Authors may also request that certain (but not more than three) reviewers not be chosen.
The cover letter should be submitted as a Microsoft Word (.doc) file (smaller than 1 MB) at the same time the work is submitted online.
6. Accepted manuscripts
Proofs. Rough galley proofs in PDF format are supplied to the corresponding author via e-mail. Corrections must be returned within 4 working days of receipt of the proofs. Subsequent corrections will not be possible, so please ensure all desired corrections are indicated. Note that we may proceed with publication of the article if no response is received.
Offprints. Twenty (20) offprints of each article are sent to the corresponding author. Additional offprints can be ordered before the article is published. Offprint requests after publication will be subject to an extra charge.
Page and color charges. A page charge of $140 will be assessed for each printed page of accepted manuscripts and $30 will be charged as a flat fee for each publication. The charge for printing of color figures is $340 for each page.
Transfer of copyrights. Upon acceptance of an article, authors will be asked to agree to a transfer of copyright. This transfer will ensure the widest possible dissemination of information. A letter will be sent to the corresponding author confirming receipt of the manuscript. A form facilitating transfer of copyright will be provided. If excerpts from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article.
Cover submissions. Authors whose manuscripts are accepted for publication in Drug Discoveries & Therapeutics may submit cover images. Color submission is welcome. A brief cover legend should be submitted with the image.


